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ForteBio Launches G Protein Biosensors for Rapid IgG Analysis

ForteBio, a global provider of label-free systems which enhances the production of pharmaceutical and biotherapeutic products, declared the release of its innovative Dip and Read G-Protein biosensor for fast identification and calibration of various sets of immunoglobulin (IgG), which is an antibody molecule, present in mammals.

The novel biosensor operates on the Octet label-free instrumentation basement permitting rapid measurements, user-friendliness and cost-effectiveness. The company has also procured ISO certification for the biosensor fabrication process.

Christopher Silva, vice president of marketing , ForteBio explained that the G-Proteins bind specifically to almost all the immunoglobulins of mammalian origin such as goat, bovine, murine and others and this unique feature allows its exploitation in the discovery of antibodies, production measurement and the development of cell lines.

Mr. Silva stated again that the conventional IgG measurement process for various species and subtypes employing G-Proteins are tedious, laborious and requires more time until recently with the advancement of this specific biosensor from ForteBio, the researchers could gain unique binding data easily and rapidly with less expenditure. The Protein biosensor can be recycled and used again for enhancing the working ability thereby reducing the expenditure, he added.

The advanced protein sensor arrives with the pre-immobilized recombinant G proteins on its periphery and can be directly utilized on the Octet equipments of ForteBio. The Octet platform is supported by the BioLayer Interferometry (BLI) technology of the company, which employs optical biosensors to monitor numerous parallel interactions without using any detection agents. The Octet platform includes eight and 16 chambered instruments that can perform 96 and 384 welled assays. The Octet devices are fabricated to make kinetic characterization and measurements easier by avoiding the output time constraints in conventional ELISA tests and SPR-based assays. The disposable Octet biosensors are designed in an ideal microplate pattern with  a proprietary bio-consistent non-denaturing even matrix  is coated over the microplate which ensures specific binding patterns.

More than 2.5 million assays have been performed using the Octet biosensors with high precision, strength and performance.  The company’s biosensor fabrication unit is ISO 9001:2008-approved for its quality delivery.


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