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SLAC’s LCLS-II Captures Ultrafast Events at Atomic Scale

Nearly a million X-ray flashes per second: SLAC’s upgraded laser and next-gen sensors are filming atoms in action, unlocking secrets of quantum leaps, chemistry, and life itself.

Georgi Dakovski, SLAC lead scientist and qRIXS instrument lead, stands beside the qRIXS instrument

Image Credit: Jacqueline Ramseyer Orrell/SLAC National Accelerator Laboratory

Recently revealed by the National Accelerator Laboratory, researchers have given the Linac Coherent Light Source (LCLS-II) at SLAC a major upgrade, one that’s redefining the limits of ultrafast science. The revamped X-ray free-electron laser now delivers nearly one million pulses per second, up from just 120, allowing scientists to capture high-speed molecular events with breathtaking clarity and speed.

But this leap isn’t just about the beam. At the core of LCLS-II’s new power is a suite of custom-built, high-efficiency photon sensors, designed to handle the laser’s intensity and turn raw pulses into detailed, real-time portraits of atomic and molecular behavior.

Why SLAC Needed This Sensor Innovation

The original LCLS enabled breakthrough science, but its relatively low repetition rate has limited the speed and resolution of experiments. Once LCLS-II could deliver X-rays at microsecond intervals, the bottleneck shifted to detection: researchers needed ultrafast, high-resolution sensors that could keep up with the data flood and resolve femtosecond timescales.

This was especially critical for techniques like resonant inelastic X-ray scattering (RIXS), which rely on precise detection of weak photon signals against noisy backgrounds. Sensors had to be both ultrafast and exquisitely sensitive, timing-synchronized as well as robust enough to handle intense photon flux without data degradation.

Inside the Detector 

The sensors powering LCLS-II’s new instruments, in particular the qRIXS and chemRIXS platforms, are built on advanced silicon-based arrays, including back-illuminated CMOS and single-photon avalanche diode (SPAD) technologies. These systems are engineered for extreme-speed operation and minimal dead time, capturing individual photon events within nanosecond to femtosecond windows.

The new detectors combine single-photon sensitivity with quantum efficiency exceeding 80 % across relevant X-ray energies. They also have gigahertz-range parallel readouts that prevent signal pile-up under high flux. They are also equipped with high-speed analog-to-digital converters and low-noise amplification circuitry to ensure accurate signal capture. 

Finally, cryogenic cooling systems minimize thermal noise and dark counts, preserving fidelity even under demanding experimental conditions. 

Phase-locked loops and real-time feedback electronics handle synchronization, keeping detector timing aligned with the LCLS-II pulses at femtosecond precision. Signal processing algorithms filter noise, identify photon events, and apply centroid localization for high spatial resolution. Additionally, micro-patterned readout structures allow angular distribution measurements of scattered particles, enabling researchers to accurately resolve subtle physical interactions.

From Femtoseconds to Frame-by-Frame Molecular Movies

These sensors do more than keep pace; they are redefining what’s possible. With their heightened sensitivity and precision, researchers can now record molecular movies: high-resolution, time-resolved visualizations of atomic motion, electron hopping, bond breaking, and quantum state transitions.

Processes that once took hours or days to capture are now observable in seconds, cutting experiment times and enabling more dynamic, iterative investigations. Scientists can now scan more parameters, track transient states, and study rare events with a level of fidelity previously unattainable.

Importantly, the detectors can handle intense X-ray fields without saturating, preserving signal integrity even in low-concentration or weakly scattering samples, which is key for studying dilute biological systems and complex quantum materials.

What This Means

With its new suite of detectors, LCLS-II is already changing how researchers examine the fastest and most fundamental processes in nature.

The advance is expected to speed progress across disciplines, including materials science, energy research, structural biology, and quantum chemistry. The upgraded sensors are central to this shift, turning once-invisible processes into observable events, with both clarity and precision.

The Atom, in Motion and in Focus

SLAC’s LCLS-II upgrade, backed by cutting-edge sensor engineering, marks a turning point for atomic-scale science. These tools make it possible to study nature’s fastest, faintest processes not just occasionally, but routinely.

By capturing how energy flows, bonds form and break, and particles shift in real time, the new system opens a window onto the dynamic choreography of matter itself. The result could be faster breakthroughs and a crystal clear view of the atomic world.

Reference

Press Release. Stanford Report. New X-ray laser toolkit advances study of nature’s mysteries. Accessed on 7th August 2025. https://news.stanford.edu/stories/2025/08/x-ray-laser-upgrade-slac-atomic-molecular-research

Dr. Noopur Jain

Written by

Dr. Noopur Jain

Dr. Noopur Jain is an accomplished Scientific Writer based in the city of New Delhi, India. With a Ph.D. in Materials Science, she brings a depth of knowledge and experience in electron microscopy, catalysis, and soft materials. Her scientific publishing record is a testament to her dedication and expertise in the field. Additionally, she has hands-on experience in the field of chemical formulations, microscopy technique development and statistical analysis.    

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