Study Demonstrates Masimo SET Pulse Oximetry Has Higher SpO2 Specificity and Sensitivity

Masimo has reported the demonstration of Masimo SET pulse oximetry’s efficiency in a recent study in the Journal of Clinical Anesthesia. According to the study, Masimo Radical with Masimo SET pulse oximetry demonstrated higher oxygen saturation (SpO2) sensitivity and specificity, showing minimal failure rates with respect to motion and low perfusion compared to other new-generation pulse oximeters.

Clinicians monitor SpO2 for early detection of hypoxemia. The exceeding efficiency of Masimo SET Measure-through Motion and Low Perfusion pulse oximetry over the technological limitations of conventional pulse oximetry have been demonstrated in over 100 independent clinical studies. The precision of pulse oximetry can be adopted for enhancing true alarm detection and for minimizing the occurrence of false alarms.

Based on the study conducted at the California-based Long Beach Veterans Affairs Healthcare System, researchers carried out an assessment on 10 healthy volunteers. Comparative evaluation was performed with the Nellcor N-600 (OxiMax V 1.1.2.0), Masimo Radical (SET V 5.0), and the GE TruSat during induced low perfusion and motion. In order to induce low perfusion, the room temperature was reduced to 16° C – 18°C.

Calculation of sensitivity involves dividing the number of tests viz., the control device read <90%, where the test device read <90% during hypoxia. Calculation of specificity can be achieved by dividing the number of events that the control device reported values >90% and the test device also reported SpO2 values >90% during normoxia. For each device, the failure rate was calculated by dividing the time period where each instrument displayed no SpO2 value by the total time of the test.

During machine- as well as volunteer-generated motion, Masimo SET demonstrated the highest SpO2 sensitivity (100% and 95%), and maximum SpO2 specificity such as 93% and 97%, respectively. The Nellcor OxiMax showed 65% and 50% sensitivity with specificity of 67% and 77%. The GE TruSat showed 20% and 15% sensitivity and 83% and 82% of specificity.

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