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ForteBio Unveils AMC Biosensor for Kinetic Characterization of Mouse Antibodies

ForteBio, a specialist in the field of label-free technology that speeds up the development of pharmaceutical and biotherapeutic products, has introduced a new Dip and Read Anti-Mouse IgG Fc Capture (AMC) biosensor, which is used on ForteBio’s Octet Instrumentation platform.

The biosensor allows screening of mouse antibodies, high-throughput kinetic characterization and screening of other Fc-containing proteins easily and cost-effectively.

Christopher Silva, Vice President of Marketing in ForteBio, revealed that the introduction of the AMC biosensor would help researchers to benefit from the label-free biosensors during the time of discovery projects utilizing murine models and when working on human antibodies. He mentioned that the company provides Anti-Human IgG Fc Capture biosensor for analyzing human IgG antibodies. According to him, the AMC biosensor removes the labor-intensive, inconvenient steps normally related with SPR and ELISA methods for screening and kinetic characterization and thus permits research applications such as characterization and hybridoma screening. It also restricts the movement of mouse Fc-containing proteins on the biosensor from a purified or crude matrix without biotinylation. Moreover, AMC biosensors could be reused and regenerated up to 10 times.

Silva further stated that the biosensor could work with other research tools used for increasing cost efficiency, speed and ease of use. Researchers who used the Protein G biosensor to titer hybridoma samples could now utilize the AMC for performing affinity and kinetics analysis on the epitopes of interest from the same crude sample.

Source: http://www.fortebio.com

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